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    Webinaire à la demande

    Prefilled Ophthalmic Syringes
    New Possibilities in Terminal Sterilization

    Personnel de Sterigenics
    January 24, 2024 | Presenter(s): Eric Offermann, Sterigenics, Bernd Zeiss, Gerresheimer

    In this joint webinar, Eric Offermann and Bernd Zeiss speak about Nitrogen Dioxide (NO2) as a new sterilization method and an alternative to EtO gas. A joint study carried out by Gerresheimer, Sterigenics and Früh, shows that NO2 is well suited to terminally sterilize prefilled ophthalmic syringes. The following topics will be addressed in detail:

    • Comparison of EtO vs. NO2 penetration into the filled syringe.
    • Analyze gas ingress through different plunger stoppers including silicone oil-free and standard rubber plungers.
    • Scrutinize gas ingress through two different cap designs based on different elastomer properties.
    • Investigate gas permeation through COP plastic barrels compared to glass.
    • Check if the final blister has an influence on either sterilization method.

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